\begin{tikzpicture}

\definecolor{darkgray176}{RGB}{176,176,176}
\definecolor{steelblue31119180}{RGB}{31,119,180}

\begin{axis}[
date coordinates in=x,
tick align=outside,
tick pos=left,
x grid style={darkgray176},
xmin=2016-10-10 17:59, xmax=2016-10-10 18:15,
xtick style={color=black},
y grid style={darkgray176},
ymin=49.999, ymax=50.021,
ytick style={color=black}
]
\addplot [semithick, steelblue31119180]
table [header=false,col sep=comma] {%
2016-10-10 18:00,50
2016-10-10 18:15,50.02
};
\end{axis}

\end{tikzpicture}
